A Rapid Interfacial Route to Produce Water Dispersible Nanoparticles
This invention describes a simple direct route by which water-dispersed nano-particles can be prepared. Water-oil dispersions with nanoparticles, the elemental composition of which allows the attachment of oil-soluble ligands, are shown to undergo a process at the oil-water interface that imparts a water solubility to the particles. The nanoparticles are photoluminescent in both the oil-soluble and water soluble states.
Nanoparticle based materials, especially those with active electronic and luminescent properties, are attracting interest as components in biotechnology for use as fluorescent tags in diagnostics and detection of disease. Nanoparticles of different sizes differ in emission wavelength, opening opportunities to perform complex biological studies based on this precise detection mechanism.
Production of water-soluble nanoparticles by an interfacial process, which overcomes previous limitations that require multiple preparative steps to achieve water solubility.
Patent Issued US 7,470,840
Ling X. Shen, Ph.D., MBA
Commercial Ventures and Intellectual Property