Perry Research Group

Welcome to the Perry Lab

Perry Research Group

Research in the Perry laboratory utilizes self-assembly, molecular design, and microfluidic technologies to generate biomimetic microenvironments to study and enable the implementation of biomolecules to address real-world challenges. Individually, microfluidics represents an enabling technology for high throughput analyses such as the time-resolved structural analysis of enzyme dynamics, while control over molecular interactions in self-assembling polyelectrolyte systems can be used to examine the interplay between biomolecules and the environment. Together, these capabilities can be coupled to generate artificial organelles for use in applications ranging from biochemistry to bioenergetics, biocatalysis, and biomedicine. Furthermore, this work has tremendous pedagogical potential to inspire students to work at the intersection of chemistry, biology, and engineering.

News and Announcements

October 5th, 2017

A UMass news story featured Prof. Jessica Schiffman and Prof. Perry for their work on developing green, non-toxic nanofiber fabrics for a wide range of uses, alongside a beautiful SEM image from Zoey Meng that was colored by Savannah Szemethy!

September 23rd, 2017
Svilen Kolev

Welcome to Svilen Kolev, a junior in Chemical Engineering who will be working in collaboration with Prof. Anne Gershenson from the Department of Biochemistry and Molecular Biology on a project to use microfluidics to study protein folding diseases.

September 20th, 2017

Congratulations to Yalin Liu on the publication of her paper examining the rheology of salt-driven liquid-to-solid transitions in complex coacervates!

"Rheological Characterization of Liquid-to-Solid Transitions in Bulk Polyelectrolyte Complexes," Y. Liu, B. Momani, H.H. Winter, S.L. Perry, Soft Matter, (2017), 13, 7332-7340. [PDF]

September 15th, 2017

Congratulations to Brandon Johnston and Cameron Johnston on the publication of their paper on the effect of comb vs. linear architecture on complex coacervation!

"The Effect of Comb Architecture on Complex Coacervation," B.M. Johnston, C. W. Johnston, R. A. Letteri, T.K. Lytle, C.E. Sing, T. Emrick, S.L. Perry, Organic and Biomolecular Chemistry, (2017), 15, 7630-7642. [PDF]

September 7th, 2017
Lila Durán Ruiz

Welcome to Lila Durán Ruiz, a sophomore in Chemical Engineering who will be working on the incorporation of conjugated polymers into complex coacervates.

August27, 2017
Charles Sing

Our collaborator, Prof. Charles Sing just published an exciting new paper on the theory of complex coacervation!

"Transfer Matrix Theory of Polymer Complex Coacervation," T.K. Lytle and C.E. Sing, Soft Matter, (2017). [PDF]

August 22nd, 2017
Li-Wei Chang

Li-Wei Chang gave a fantastic presentation on Sequence and Entropy-based Control of Complex Coacervation at a special PMSE symposium on Polyelectrolytes, Coacervates, Precipitates and Multilayers at the ACS Annual Meeting in Washington DC!

August 21st, 2017

Congratulations to our new Chemical Engineering Colleague Ashish Kulkarni on being named one of C&EN's Talented 12 for 2017!

August 21st, 2017

Congratulations to my good friend and colleague from graduate school Fikile Brushet on being named one of C&EN's Talented 12 for 2017!

August 14th, 2017

Congratulations to Kush Basu, Tyler Carpenter, and Brandon Johnston on having been awarded Research Grants from the Commonwealth Honors College in support of their senior theses!

August 14th, 2017

Congratulations to Savannah Szemethy, Matt Labbe, and Bryan Chua, and on having been awarded Research Assistant Fellowships from the Commonwealth Honors College!

July 27th, 2017

Zoey's recent article in ACS Macro Letters on electrospinning of complex coacervation was highlighted in Biotech Week!

July 17th, 2017
Bryanne Zonghi

Welcome to Bryanne Zonghi, a rising junior in Chemical Engineering who will be working on particle-based complex coacervates.

July 13th, 2017
Sarah Perry

Prof. Perry presented on Graphene Microfluidics for Room Temperature Crystallography at the 91st ACS Colloid and Surface Science Symposium.

July 11th, 2017
Zoey Meng

Zoey Meng presented both a poster and a presentation on Encapsulating Cargo Using Electrospun Complex Coacervates Fibers at the 91st ACS Colloid and Surface Science Symposium.

June 29th, 2016

Congratulations to Whitney Blocher on having her review paper formally come out!

"Biomimetic Complex Coacervate-Based Materials for Biomedicine," W.C. Blocher, S.L. Perry, WIREs Nanomedicine and Nanobiotechnology (2017), 9(4), e1442. [PDF]

June 23th, 2017
Sarah Perry
June 6th, 2017
Sarah Perry

Prof. Perry will be tomorrow presenting on Ultra-Low Background Graphene Microfluidics at a workshop on the Emerging Frontiers in Biology using Synchrotron Radiation at the 2017 CHESS User's Meeting. Check it out live on Youtube!

May 24th, 2017
Caleb Boucher

Welcome to Caleb Boucher, a rising junior in Chemical Engineering who will be working on a joint project with the Schiffman Lab on the development of films and fibers from polyelectrolyte complexes.

May 19th, 2017
Tyler Carpenter

Congratulations to Tyler Carpenter, who will be working at SWM in Greenfield, MA this summer as a safety engineer!

May 17th, 2017
Shuo Sui

Congratulations to Shuo Sui, who was named as one of the Spring 2017 Tillwick and Eldridge Teaching Assistant Award winners for his efforts in CHEM-ENG 590E: Microfluidics and Microscale Systems in Materials in Biology!

May 15th, 2017
Adam Murphy

Congratulations to Adam Murphy, who will be joining OpGen as a Research and Development Associate Engineer after graduation!

May 15th, 2017
Sarah Perry

Prof. Perry will be presenting on Ultra-Low Background Graphene Microfluidics at a workshop on the Measurement and Interpretation of Diffuse Scattering in X-Ray Diffraction for Macromolecular Crystallography at the NSLS II and CFN Users’ Meeting at Brookhaven National Laboratory.

May 13th, 2017
2017 Seniors

Congratulations to Perry group members Rasmia Shamsi, Christine Davis, Alex Brosseau, Adam Murphy, and Cristina Vieira Robalo, graduating seniors from the class of 2017

May 9th, 2017
Sarah Perry

Prof. Perry presented on Graphene Microfluidics for Room Temperature Crystallography at the Symposium on Synchrotron-Based Drug Discovery: The Next 25 Years at the APS/CNM Users’ Meeting at Argonne National Laboratory.

May 9th, 2017
Rasmia Shamsi

Congratulations to Rasmia Shamsi, who will be joining United Technologies after graduation!

May 9th, 2017
Christine Davis

Congratulations to Christine Davis, who will be joining Shire Pharmaceuticals after graduation!

May 9th, 2017
Alex Brosseau

Congratulations to Alex Brosseau, who will be joining Mylan Technologies as a Chemist after graduation!

May 2nd, 2017

Prof. Perry was awarded a collaborative research grant from the NSF BioXFEL STC to develop next-generation graphene-based microfluidics for applications in advanced structural biology!

April 28th, 2017
Christine, Rasmia, Brandon

Rasmia Shamsi, Christine Davis, and Brandon Johnston will be presenting their research at the 23rd Annual Undergraduate Research Conference!

April 25th, 2017
Sarah Perry

Prof. Perry is one of two people honored this year as Outstanding Teachers in the College of Engineering!

April 20th, 2017

Congratulations to Zoey Meng on the publication of her first paper describing the electrospinning of complex coacervates to form ultra-stable fibers!.

"Complex Coacervation: Chemically Stable Fibers Electrospun from Aqueous Polyelectrolyte Solutions," X. Meng, S.L. Perry, J.D. Schiffman,ACS Macro Letters, (2017), 6, 505-511. [PDF]

April 20th, 2017
MRS Logo

Prof. Perry will be giving an invited talk on Molecular Engineering Polyelectrolyte Complex Materialsin a symposium on Aqueous Cytomimetic Materials at the Spring MRS Meeting in Phoenix.

April 7th, 2017

Our review article on "Microfluidics: From Crystallization to Serial Time-Resolved Crystallography," was just accepted for publication as part of a special ACA Transactions issue of Structural Dynamics.

"Microfluidics: From Crystallization to Serial Time-Resolved Crystallography," S. Sui, S.L. Perry, Structural Dynamics, (2017) 4(3), 032202. [PDF]

April 2nd, 2017
ACS Logo

Prof. Perry will be presenting two talks at the ACS National Meeting this week in San Francisco. Her first talk, on Material Dynamics in Complex Coacervates will be in a special symposium on Complex Coacervation. Her second talk will be on Patterning and Structure in Polypeptide-based Coacervates in a symposium on Molecular Engineering of Peptide Assembly.

March 28th, 2017

Congratulations to Yalin Liu, Kush Basu, and Rasmia Shamsi on the publication of a paper in collaboration with Prof. Charles Sing!

"Molecular Connectivity and Correlation Effects on Polymer Coacervation," M. Radhakrishna, K. Basu, Y. Liu, R. Shamsi, S.L. Perry, C.E. Sing, Macromolecules, (2017) 50(7), 3030–3037. [PDF]

March 24th, 2017

Prof. Perry will be presenting on the Molecular Design of Polyelectrolyte Complexes at the first ever PanPoly Meeting in Guaruja, Brazil.

March 20th, 2017

Congratulations to Savannah Szemethy! Her submission to the Science as Art competition at the Spring MRS Meeting was selected as a finalist!

March 16th, 2017

Prof. Perry and our collaborators from Prof. Charles Sing's Lab will be presenting at a symposium on Polyelectrolyte Complexation today at the APS March Meeting.

March 4th, 2017
Rebecca Hershman

Congratulations to Rebecca Hershman on being invited to participate in a summer REU experience at from the Functional Materials and Manufacturing Institute at the University of South Florida!

February 23rd, 2017
Xi Hao

Welcome to Xi "Ryan" Hao, a junior in Chemical Engineering who will be working on using complex coacervates as oxygen barriers in graphene microfluidics.

February 20th, 2017
Brandon Johnston

Congratulations to Brandon Johnston on his upcoming summer internship at Illumina, where he will be working on science related to DNA sequencing!

February 16th, 2017

Our review article on the Linear Viscoelasticity of Complex Coacervates was just published as part of a special issue of Advances in Colloids and Interface Science on complex coacervation!

February 14th, 2017
Charles Sing

Congratulations to our collaborator, Prof. Charles Sing at the University of Illinois Urbana-Champaign on having been awarded an NSF CAREER Award on Developing the design rules of charge sequence to inform polymer self-assembly!

February 14th, 2017
Matt Labbe

Welcome to Matt Labbe, a freshman in Chemical Engineering who will be studying the rheology of complex coacervates.

February 5th, 2017
Elizabeth Voke

Welcome to Elizabeth Voke, a freshman in Chemical Engineering who will be working on understanding charge patterning in complex coacervation.

February 2nd, 2017

A collaborative paper with Prof. Shelly Peyton on the use of Wikipage-based course textbooks was just published!

"A Student-Created, Open Access, Living Textbook," S. Galarza, S.L. Perry, S. R. Peyton, Chemical Engineering Education, (2017) 51(1), 2-9. [PDF]

January 29th, 2017
Rachel Brody

Welcome to Rachel Brody, a junior in Biology who will be working on understanding protein encapsulation and stabilization in complex coacervates.

January 12th, 2017
Brenna Walsh

Best wishes to Brenna Walsh on the pursuit of a Math degree!

January 11th, 2017

Our joint project with the Klier lab and Camco Corporation to decrease the methanol content in windshield washer fluid was highlighted at UMass-Lowell!

January 2nd, 2017
Sarah Perry

Prof. Perry will be giving a seminar on Nature-Inspired Molecular Engineering of Polyelectrolyte Complex Materials in the Department of Chemical Engineering at WPI on Wednesday, January 18th.

See more news from 2016, 2015 and 2014.