Perry Research Group

Welcome to the Perry Lab

Perry Research Group

Research in the Perry laboratory utilizes self-assembly, molecular design, and microfluidic technologies to generate biomimetic microenvironments to study and enable the implementation of biomolecules to address real-world challenges. Individually, microfluidics represents an enabling technology for high throughput analyses such as the time-resolved structural analysis of enzyme dynamics or the continuous manufacture of RNA. At the same time, control over molecular interactions in self-assembling polyelectrolyte systems can be used to examine the interplay between biomolecules and the environment. Together, these capabilities can be coupled to generate artificial organelles for use in applications ranging from biochemistry to bioenergetics, biocatalysis, and biomedicine. Furthermore, this work has tremendous pedagogical potential to inspire students to work at the intersection of chemistry, biology, and engineering.

News and Announcements

January 17th, 2025
Prof. Sarah Perry

Prof. Perry will be giving a seminar on Polyelectrolyte Complex Materials in the Department of Chemical and Biological Engineering at Colorado School of Mines.

January 16th, 2025
Dr. Isaac Ramírez Marrero

Best wishes to Dr. Isaac Ramírez Marrero as he ends his time with us in the Perry lab and starts his new journey as a postdoctoral researcher at the University of Illinois at Urbana-Champaign working with Prof. Antonia Statt and Prof. Simon Rogers!

January 14th, 2025
NextFlex WISE

Check out this video put together by the NextFlex Women in STEM Education program!

January 3rd, 2025
2025 AFD-X Chips

Congratulations to Dr. Sarthak Saha and Yaozu Chen on the publication of their new paper!

"Scalable Fabrication of Array-Type Fixed-Target Device for Automated Room Temperature X-ray Protein Crystallography," S. Saha, Y. Chen, S. Russi, D. Marchany-Rivera, A.E. Cohen, S.L. Perry, Scientific Reports, (2025), 15, 334. [PDF]

January 1st, 2025
Dr. Sarthak Saha

Best wishes to Dr. Sarthak Saha as he ends his time here in the Perry lab and starts his new journey as a postdoctoral researcher the lab of Dr. Avanish Mishra at Harvard Medical School and Massachusetts General Hospital!

December 20th, 2024
2025 Carbon Dot Coacervates

Congratulations to Dr. Pankaj Pandey, Arvind Sathyavageeswaran, and Nick Holmlund on the publication of their new paper!

"Polyelectrolyte-Carbon Dot Complex Coacervation," P.K. Pandey, A. Sathyavageeswaran, N. Holmlund, S.L. Perry, ACS Macro Letters, (2025), 14(1), 43-50. [PDF]

December 6th, 2024
Isaac Ramírez Marrero Dissertation Art

Congratulations to Dr. Isaac Ramírez Marrero for successfully defending his PhD dissertation on Polyelectrolyte Complex Materials: Design Rules and Applications!!! Dr. Ramírez Marrero is the eighth PhD student to graduate from the Perry lab!

November 26th, 2024
Vaishnavi Mahankal

Welcome to Vaishnavi Mahankal, a first year PhD student who will be us joining to work on microfluidics for time-resolved crystallography!

November 24th, 2024
Jina Lee

Welcome to Jina Lee, a junior in Engineering Sciences at Smith College who will be joining us in the lab over winter break!

November 20th, 2024
Whitney Blocher McTigue

Congratulations to Prof. Whitney Blocher McTigue, who was awarded the Lehigh Early Career Teaching Award for her outstanding impact and dedication to student success!

November 18th, 2024
Yaozu Chen

Check out this UMass Engineering News Story about Yaozu Chen's award for best poster at the 2024 AIChE Annual Meeting!

November 17th, 2024
Dr. Sonu Kizhakkepura

Best wishes to Dr. Sonu Kizhakkepura as he ends his time at UMass and moves on to a bright future!

November 14th, 2024
Dr. Sonu Kizhakkepura

Congratulations to Dr. Sonu Kizhakkepura on winning 1st Place in the poster competition at the 12th International mRNA Health Conference!

November 14th, 2024
Diwakaran Rathinam Palaniswamy

Congratulations to Diwakaran Rathinam Palaniswamy on winning 1st Place in the poster competition at the 12th International mRNA Health Conference!

November 5th, 2024
Baktha Kannadasan

Baktha gave both a talk and a poster on Polymer-based Microfluidic Chips for Time-resolved Serial Crystallography at the 18th International Conference on the Crystallization of Biological Macromolecules (ICCBM).

November 4th, 2024
Prof. Sarah Perry

Prof. Perry presented a keynote lecture on Microfluidics for Structural Biology at the 18th International Conference on the Crystallization of Biological Macromolecules (ICCBM).

See more news from 2024.