Neuroscience and Behavior Program

 

 

     

 

 

 
 
 
 
 
 
 
 
 
 
 
 
 
 

 

Retinal afferents to the dorsal raphe nucleus

 

Retinal afferents to the dorsal raphe nucleus


This is a darkfield photomontage showing cholera toxin B - immunoreactive optic axons (arrows) emerging from the gerbil optic tract (OTr) at the level of the rostral superior colliculus (SC). These axons course medially through the commissure of the superior colliculus (CSC), descend through the periaqueductal gray, and ultimately terminate in the serotonergic dorsal raphe nucleus (DRN) (not shown). Studies in the Fite laboratory are aimed at understanding the neuroanatomical organization and functional significance of this unusual retinal-brainstem projection, as well as determining how light stimulation may influence the activity of DRN neurons over the diurnal cycle and during experimentally controlled visual stimulation.