| The plasma
membrane serotonin transporter (SERT) is selectively expressed
by serotonergic neurons and is responsible for serotonin (5-HT)
reuptake after its release into the synaptic cleft. In the Meyer
laboratory, we have been studying the neurotoxic effects
of MDMA (“Ecstasy”) on the serotonergic system at
different stages of postnatal development in rats. Immunocytochemistry
for SERT (as a marker for serotonergic fibers) is one of several
methods we use to assess MDMA-induced damage to this neurotransmitter
system. |
