Eric Martz



B.A., 1963, Oberlin College
Ph.D., 1969, Department of Biology, Johns Hopkins University
Postdoctoral, 1970, Department of Biology, Princeton University
Postdoctoral, 1971-1972, Department of Pathology, Harvard Medical School

Professional Appointments

Harvard Medical School, Assistant Professor of Pathology, 1974
Harvard Medical School, Associate Professor of Pathology, 1977
University of Massachusetts, Amherst, Associate Professor of Microbiology, 1981-1992.
University of Massachusetts, Amherst, Professor of Microbiology, 1992-2003.
University of Massachusetts, Amherst, Professor Emeritus, 2004-present.

Research Awards

National Science Foundation, 1991-1995. Regulation of Leukocyte Adhesion Receptor Function.
National Science Foundation, 1985-1988. Virus Destruction Mechanisms of Killer T Lymphocytes.

Research Interests

Until 1997: Mechanisms of cellular immunity, especially interactions of cytotoxic T-lymphocytes (CTL) with target cells; role and regulation of LFA-1 integrin in lymphocyte adhesions.

Since 1997: Macromolecular visualization and structural bioinformatics.

Three cytotoxic T lymphocytes (smaller cells) attacking two tumor cells. (Scanning electron micrograph by M. Levinthal, M.J. Karnovsky, and E. Martz, ca. 1975, unpublished.)

Selected Publications

Martz, E. 1993. Overview of CTL-target adhesion and other critical events in the cytotoxic mechanism. In: "Cytotoxic cells: recognition, effector function, generation, and methods," Sitkovsky, M.V.; Henkart, P.A., eds., Birkhä user; Boston, MA, USA, pp. 9-45.

Martz, E. and S.R. Gamble. 1992. How do CTL control virus infections? Evidence for prelytic halt of Herpes simplex. Viral Immunology 5:81-91.

Martz, E. and Howell, D.M. 1989. CTL: virus control cells first and cytolytic cells second? DNA fragmentation, apoptosis, and the prelytic halt hypothesis. Immunol. Today 10:79-86.

Martz, E. 1987. LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes. Human Immunol. 18:3-37.

Henkart, P. and E. Martz, eds. 1985. Mechanisms of Cell-Mediated Cytotoxicity II, Plenum Press, NY, 568 pages. (Proceedings of the 2nd International Workshop on Mechanisms of Cell-Mediated Cytotoxicity; Adv. Exp. Med. Biol. Volume 184).
All Publications

Web and Email List Projects 1995-1997.