Here is the backbone of lysozyme. The epitope which binds to IgG1-kappa D1.3 is thickened. In another view (not shown) it can be seen that the epitope forms a relatively flat surface. Notice how the epitope is discontinuous, that is, made up of loops of the protein which are proximal in the native structure, but are not sequential in the amino acid sequence. This image uses RasMol's "group" coloring scheme, in which the backbone is colored in rainbow sequence from one end to the other.

This image was constructed from images in a RasMol "movie" script. The atomic coordinate file employed is 1FDL.PDB.


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