Volunteer Opportunities


The Muscle Biology and Imaging Lab at the University of Massachusetts Amherst regularly seeks individuals to participate in research studies. View current volunteer opportunities.

Awards and Honors


View awards and honors received by MBIL graduate students.

MBIL Alumni


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Department and College


Ling Xin, M.S.

Graduate Research Assistant
(413) 545-6072
lxin@kin.umass.edu

I am currently a 3rd year graduate student working towards my doctorate in Kinesiology. In the past two years, I was study coordinator for a human subject study that examined the effects of two botanical supplements on gene expression in response to exercise stress.  I am analyzing the microarray data using Ingenuity Pathway Analysis (IPA) to discover gene expression that may be altered by these supplements.    

Prior to entering this lab, I received my Bachelor’s degree in Clinical Medicine from China and my Master’s degree in Molecular and Cellular Biology from University of Massachusetts Amherst. The title of my Master thesis was: Stability of the frog motor nerve terminal: roles of perisynaptic Schwann cells and muscle fibers. I was excited to join Dr. Clarkson’s lab because of the opportunity to work with human subjects. I am happy and proud of being a member of this lab group. I look forward to continuing to learn and improve my knowledge of molecular mechanisms underlying exercise-induced muscle damage.  

During my spare time, I enjoy reading, listening to music and spending time with my family & friends.  

Abstracts

1. L. Xin,  S. Ramakrishnan, R.D. Hyldahl, K.L. Riska, S. Chipkin,  M.J. Hubal,  M. A. Murray, V. Greger, P. Prabhakar, K. Shaver, P.M. Clarkson, The effects of two botanical supplements on gene expression following eccentric exercise. Medicine and Science in Sport and Exercise. 42(5) Supplement, May 2010 [Abstract]

2. R.D. Hyldahl, S. Ramakrishnan, L. Xin, K.L. Riska, S. Chipkin, M.A. Murray, V. Greger, P.Prabhakar, K. Shaver P.M. Clarkson, Two Botanical Supplements with Antioxidant and Anti-inflammatory Properties Protect Against Eccentric Exercise-Induced Strength Loss. Medicine and Science in Sport and Exercise. 42(5) Supplement, May 2010 [Abstract]

3. K.L. Riska, S. Ramakrishnan, L.Xin, R.D.Hyldahl, S. Chipkin,  B.Rahmberg, M.J. Hubal,  M.A. Murray, V.Greger, P.Prabhakar, K.Shaver, P.M. Clarkson, Gene expression profiling of skeletal muscle after eccentric exercise. Medicine and Science in Sport and Exercise. 42(5) Supplement, May 2010 [Abstract]

Presentations

1. L. Xin The effects of two botanical supplements on gene expression following eccentric exercise. American College of Sports Medicine Annual Meeting, June 2010 – Baltimore, MD (Poster presentation)

2. L. Xin Effects of two botanical supplements on gene expression following eccentric exercise. NEACSM Annual Meeting, 2009 – Providence, RI (Slide presentation)

3. Effects of two botanical supplements on gene expression following eccentric exercise. Graduate Seminar. Amherst, MA. November 2009

Muscle Response Research

Activation of NF-kb in cells outside the myofiber boundary, 3h following eccentric exercise (ECC). A. Confocal images of triple stained 10µm sections from a representative ECC sample for dystrophin (dys=blue), the p-65 subunit of NF-kb (p65=green) and nuclei (topro3=red). White square in merged image denotes the boundaries of the inset image. Scale bar in top 3 images and merged image = 20µm; scale bar in inset image = 10µm. Read the abstract.

Resistance Exercise and Cancer

Dr. Clarkson's research on resistance exercise during breast cancer treatment is featured in Medical Hypothesis, a journal of theoretical papers in the biomedical sciences. Read the abstract.

Rhabdomyolysis

Rhabdomyolysis is a serious, potentially life-threatening condition that can develop unexpectedly under supervised conditions. Dr. Clarkson's 2009 paper in The Journal of Strength and Conditioning Research examines a case of rhabdomyolysis in a healthy, fit 18-year-old placekicker following a supervised practice session led by the team's strength and conditioning coach. Following eight days of hospitalization with intravenous fluids, the patient recovered without complications. View the full abstract.