J. Richard Pilsner
Research areas include reproductive health and environmental epigenetics.
Our research intersects environmental toxicology, epidemiology and reproductive health with a particular emphasis on epigenetic mechanisms. Specifically, we aim to understand the role of sperm epigenetics as a mechanism linking paternal environmental exposures to reproductive and subsequent offspring health. The centerpiece of this research is the population-based study, Sperm Environmental Epigenetics and Development Study (SEEDS). This study, in collaboration with Baystate Reproductive Medicine at Baystate Medical Center, Springfield, MA, investigates the associations between paternal environmental exposure (e.g., endocrine disrupting compounds (EDCs)), sperm epigenetics and reproductive health indices such as sperm quality and embryo development among 250 subfertile couples seeking in vitro fertilization (IVF). In parallel with the goals of SEEDS, research is also focused on advancing methodological approaches for sperm epigenetics research. To complement our human research, we are also investigating the role of paternal environmental exposures on sperm epigenetics in rodent model systems.
Learn more at https://www.pilsnerlab.com
- BA Hamline University, 1995
- MPH Columbia University, 2004
- PhD Columbia University, 2007