Heart association awards research grant to Debold

Edward Debold, assistant professor in the Department of Kinesiology, has received a three-year, $197,294 American Heart Association Scientist Development Grant to study the molecular mechanisms that underlie heart failure during heart attacks.

For his project, “The Molecular Basis of Depressed Cardiac Contractility During Acute Myocardial Ischemia,” Debold will use the single molecule laser trap and in vitro motility assays to determine the effect that ischemic conditions have on the ability of the heart’s molecular motor, myosin, to generate force and motion. Ultimately, the findings will improve understanding of myocardial ischemia and reveal new therapeutic targets for agents capable of reversing the devastating consequences of the highly prevalent condition.

June 24, 2009.