Representative Publications

Hoerner J.K., Xiao H., Kaltashov I.A. Structural and dynamic characteristics of a partially folded state of ubiquitin revealed by hydrogen exchange mass spectrometry Biochemistry (2005) 44, 11286-11294

Kaltashov I.A., Mohimen A. Estimates of protein surface areas in solution by electrospray ionization mass spectrometry Anal. Chem. (2005) 77, 5370- 5379

Igor A. Kaltashov, Stephen J. Eyles. Mass Spectrometry in Molecular Biophysics: Conformation and Dynamics of Biomolecules John Wiley & Sons Inc; January 5, 2005

Xiao H., Kaltashov I.A. Transient structural disorder as a facilitator of protein-ligand binding: Native H/D exchange-mass spectrometry study of cellular retinoic acid binding protein I J.Am. Soc. Mass. Spectrom. (2005) 16, 869-879

Hui X., Hoerner J.K., Eyles S.J., Dobo A., Voigtman E., Mel'Cuk A.I., Kaltashov I.A Mapping protein energy landscapes with amide hydrogen exchange and mass spectrometry: I. A generalized model for a two-state protein and comparison with experiment Prot. Sci. (2005) 14, 543-557

I.A. Kaltashov. Probing protein dynamics and function under native and mildly denaturing conditions with hydrogen exchange and mass spectrometry. Int. J. Mass Spectrom. (2005) 240, 249-259

I.A. Kaltashov, S.J. Eyles, H. Xiao. Combination of protein hydrogen exchange and tandem mass spectrometry as an emerging tool to probe protein structure, dynamics and function. In: Focus on Protein Research J.W. Robinson, ed. Hauppauge, New York: Nova Science Publishers, Inc., 2004, pp. 191-218

M. Zhang, D.R. Gumerov, A.B. Mason, I.A. Kaltashov. Indirect detection of protein-metal binding: Interaction of serum transferrin with In3+ and Bi3+. J. Am. Soc. Mass Spectrom. 2004 15, 1658-1664

S.J. Eyles, I.A. Kaltashov. Methods to study protein dynamics and folding by mass spectrometry. Methods (2004) 34, 88-99

Hoerner JK, Xiao H, Dobo A, Kaltashov IA. Is There Hydrogen Scrambling in the Gas Phase? Energetic and Structural Determinants of Proton Mobility within Protein Ions. J Am Chem Soc. (2004) 126, 7709-7717.

W.P. Griffith, I.A. Kaltashov. Highly asymmetric interactions between globin chains during hemoglobin assembly revealed by electrospray ionization mass spectrometry. Biochemistry (2003) 42, 10024-10033.

A. Mohimen, A. Dobo, J.K. Hoerner, I.A. Kaltashov. A chemometric approach to detection and characterization of multiple protein conformers in solution using electrospray ionization mass spectrometry. Anal. Chem. (2003) 75, 4139-4147.

D.R. Gumerov, A.B. Mason, I.A. Kaltashov. Inter-lobe communication in human serum transferrin: metal binding and conformational dynamics investigated by electrospray ionization mass spectrometry. Biochemistry (2003) 42, 5421-5428.

H. Xiao, S.J. Eyles, I.A. Kaltashov. Indirect assessment of small hydrophobic ligand binding to a model protein using a combination of ESI MS and HDX/ESI MS. J. Am. Soc. Mass Spectrom. (2003) 14, 506-515.

I.A. Kaltashov, S.J. Eyles. Studies of biomolecular conformations and conformational dynamics with mass spectrometry. Mass Spectrom. Rev. (2002) 21, 37-71.

I.A. Kaltashov, S.J. Eyles. Crossing the phase boundary to study protein dynamics and function: combination of amide hydrogen exchange in solution and ion fragmentation in the gas phase. J. Mass Spectrom. (2002) 37, 557-565.

D.R. Gumerov, A. Dobo, I.A. Kaltashov. Protein ion charge state distributions in ESI MS: distinguishing "conformational" contributions from masking effects, Eur. J. Mass Spectrom. (2002) 8, 123-130.

A. Dobo, I.A. Kaltashov. Detection of multiple protein conformational ensembles in solution via deconvolution of charge state distributions in ESI MS. Anal. Chem. (2001) 73, 4763-4773.

D. Gumerov, I.A. Kaltashov. Dynamics of iron release from transferrin N-lobe studied by electrospray ionization mass spectrometry. Anal. Chem. (2001) 73, 2565-2570.

S.J. Eyles, P. Speir, G. Kruppa, L.M. Gierasch, I.A. Kaltashov. Protein conformational stability probed by Fourier transform ion cyclotron resonance mass spectrometry. J. Am. Chem. Soc. (2000) 122, 495-500.