ANIRBAN MOHIMEN

    mohimen@chem.umass.edu

 

SUMMARY

Analytical chemist and a chemical engineer with experience in pharmaceutical industry product analysis and development.  Broad understanding of analytical instrumentation and methods with emphasis on protein analysis.  Strong interdisciplinary skills encompassing chemical engineering and chemistry.    

 

EDUCATION

Candidate for Doctorate in Chemistry:  May 2004

·  University of Massachusetts at Amherst:  September 1999 to Present

 

Candidate for a Second Bachelor in Chemical Engineering:  January 2004

· University of Massachusetts at Amherst:  September 2001 to Present

 

RELEVANT

EXPERIENCE

DOCTORATE RESEARCH   September 1999 to Present

University of Massachusetts at Amherst, Amherst, MA

· Application of mass spectrometry to study protein dynamics and conformations.

·  Analysis of proteolitic fragments using data base searches using both top down and bottoms up approach.

· Experience of using various types of mass spectrometer such as EI, FAB, ESI, MALDI, and FTMS.

· Mathematical and chemometric approaches to analyzing mass spectral data.

· LC-MS method development for analysis of bio-molecules such as proteins, lipids and drug molecules.

· Acquired valuable leadership and managing skills interacting with undergraduate researchers and visiting scholar.

 

 

SUMMER RESEARCH INTERNSHIP   June 2000 to August 2000

Pfizer Global Manufacturing, Groton, CT

·  Division of Quality Control and Quality Assurance

·  Investigated product intermediates in chemical processes

·  Interacted with manufacturing plant and quality control

· Conducted trace analysis on behalf of Pfizer’s Legal Division for investigation of patent infringement

·  Developed skills using preparative LC and Analytical HPLC-MS

·  Methods designed, developed and optimized

 

TEACHING ASSISTANT   September 1999 to May 2002

Dept. of Chemistry, University of Massachusetts Amherst, MA

·  Supervised undergraduate chemistry teaching laboratory

·  Taught undergraduate students at upper and lower level chemistry

· Designed and developed laboratory for upper level undergraduate chemistry

 

CO-OP   January 1999 to September 1999

Pfizer Central Research, Groton CT

·  Exploratory Analytical Research and Development

· Drug product testing and certification of drug product from chemical process

·  Responsible for HPLC method development and validation

·  Responsible for method development for routine drug product and drug substance analysis

·  Trained in cGMP

 

SUMMER RESEARCH INTERNSHIP   June 1998 to August 1998

Pfizer Central Research, Groton CT

·  Developed method for chiral drug product separations

· Acquired skills in High Performance Capillary Electrophoresis and    HPLC

·  Developed strong interpersonal skills in the private sector

 

UNDERGRADUATE RESEARCH February 1997 to December 1998

Dept of Chemistry, University of Massachusetts, Amherst

·  Analytical Electrophoresis of Oxalate

·  Developed research and problem solving skills in a collaborative effort with Bay State Medical Center.

 

PUBLICATIONS

           AND

PRESENTATIONS

“A Chemometric Approach to Detection and Characterization of Multiple Protein Conformers in Solution Using Electrospray Ionization Mass Spectrometry”

Anirban Mohimen, Andras Dobo, Joshua K. Hoerner, and Igor A. Kaltashov

Anal. Chem. 2003, 75, 4139-4147.

 

“A combined ESI MS/chemometric approach to study protein dynamics and shape in solution”

Anirban Mohimen, Andras Dobo, Joshua Hoerner, Igor Kaltashov
51st ASMS Conference June 2003

 

“A Novel Method of Simultaneous Charecterization of Multiple Protein Conformers in Solution Using Chemometric Approches and ESI MS”

Andras Dobo, Anirban Mohimen, Joshua Hoerner, Igor Kaltashov
50th ASMS Conference June 2002

 

“The determination of oxalate, it's precursors and metabolites in biological matrices by capillary electrophoresis (CE).”

Mohimen A, Metcalfe N.R., Uden P. C.

Abstacts of papers of the American Chemical Society.

216: 129-Anyl Part 1 Aug 23, 1998

 

AFFILIATIONS

American Chemical Society (ACS)

American Institute of Chemical Engineers (AIChE)

American Society of Mass Spectrometry (ASMS)

 

AWARDS

NIH supported Chemistry Biology Interface fellowship recipient for graduate studies (July 2002)

 

ACS Igor Koltoff Award in Analytical Chemistry 1998

 

REFERENCE

 

Available upon request