UMass Amherst
University of Massachusetts Amherst

Institute for Cellular Engineering

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ICE Research Highlights

Current Highlights

Applied Systems Biology
  Modeling Aggregation Dynamics in Taxus cuspidata Cultures
Research Highlight
  Mathematical Modeling of the Circadian Cycle in Humans
Research Highlight
  Molecular Motors: Critical Proteins in Spindle Assembly
Research Highlight
  Targeted Delivery of Therapeutic Agents to Tumors using Salmonella typhimurium
Research Highlight
  Multiscale Modeling and Analysis of Circadian Rhythm Generation and Synchronization
Research Highlight
  Adaptive evolution on complex polysaccharides using Clostridium phytofermentans
Research Highlight
  Understanding Regulation of Plant Secondary Metabolism
Research Highlight
  The role of phage in the death of Clostridium phytofermentans
Research Highlight
  Optimizing Techniques for Evaluating the Metabolic Activity of Encapsulated Cells
Research Highlight
  Flow Cytometric Characterization of Plant Cell Cultures
Research Highlight
  Glycoside Hydrolase and Sugar Transporter Regulation on Complex Substrates
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  Regulation of Paclitaxel Synthesis in Plant Cell Cultures
Research Highlight
  Islet Encapsulation: Novel Formulation Extends Islet Viability
Research Highlight
  Investigating the Effects of Cell Processing Techniques on Viability and Growth of Taxus spp. Suspension Cultures
Research Highlight
  Establishing Gene-to-metabolite Networks for Plant Signaling Compounds
Research Highlight
  Transcriptional Regulation of Cellulose Biosynthesis in Plants
Research Highlight
  Microbial species interactions facilitating anaerobic plant degradation in adapted soil communities
Research Highlight
  Modeling a Defined Mixed Culture for the Efficient Consumption of Glucose/Xylose Mixturese
Research Highlight
  Optimizing Productivity in Plant Cell Cultures through Multiscale Process Characterization and Control of Cell Aggregation
Research Highlight
  Metabolic engineering of key paclitaxel regulatory genes in Taxus spp. suspension cultures
Research Highlight
  Using Hyperthermophilic Archaea to Distill Higher Carbon Alcohols
Research Highlight
Cell Delivery
  Modified Alginate as a Potential Drug Delivery Vessel
Research Highlight
  Novel Approach to Increasing Hematopoietic Stem Cells Numbers in Culture
Research Highlight
  Engineering Cells for Novel Treatments Against Breast Cancer
Research Highlight
  Targeting drug-resistant tumor regions using engineered bacteria
Research Highlight
  Annealing Effects in PLA-PEO-PLA Hydrogels
Research Highlight
  Modeling Bacterial Surface Heterogeneity Through Polymer Adsorption
Research Highlight
  Electrostatic Model for Bacterial Adhesion
Research Highlight
  Tumor Targeting Bacteria: A New Frontier in Cancer Research
Research Highlight
  Quantifying the Effects of Precise Oxygen Delivery to Hypoxic In-vitro Tumor Tissue;
Developing Tumor Mimicking Microfluidic Bioreactors to Study Therapeutic Bacteria

Research Highlight
  Mechanical Properties of Alginate Based Interpenetrating Polymer Networks for Biomedical Applications
Research Highlight
  Selective Protein Attachment onto Nanoscale Surfaces
Research Highlight
  Redox Sensitive Polymers for siRNA Delivery
Research Highlight
  Surfaces with Antimicrobial Activity and Selective Bacterial Adhesion
Research Highlight
  Novel Hydrogel Formation Using Thiol-ene Chemistry on Norbornene-functionalized PEG
Research Highlight
  Modification of In-Vitro Tumor Spheroid Modeling Device
Research Highlight
  Design Changes in a Microfluidic Tumor-Mimicking Bioreactor
Research Highlight
  Effects of Biological Storage Conditions on Alginate Mechanical Properties
Research Highlight
  Synthesis and Characterization of Novel Biocomposites
Research Highlight
  Wound Dressings: Novel Formulations to Cut Healing Times
Research Highlight
  Surfaces for Dynamic Selective Signaling of Breast Cancer Cells
Research Highlight
  Physical Properties of Surfactant Clay Mineral Solution
Research Highlight
  Effects of Common Sterilization Methods on Mechanical Properties of Novel Alginate Hydrogels
Research Highlight
  Engineering Surfaces to Create and Utilize Dynamic and Specific Particle-Surface Interactions
Research Highlight
  Polymer-Protein Interactions for Delivery and Sensing
Research Highlight
  Biomimetic copolymers and surfactants
Research Highlight
  Characterization of Cell Penetrating Polymers Complexed with siRNA and DNA
Research Highlight
Protein Engineering
  Structural Biology of Human Lysosomal Enzymes: Insights into Human Lysosomal Storage Diseases
Research Highlight
  Towards Understanding Nonenveloped Viral Entry and Release
Research Highlight
  Bacterial Communication using a Quorum Sensing Network Research Highlight
  Construction and Evolution of Synthetic Cellular Systems
Research Highlight
  Engineering a Human Protein for Chloroplast Expression
Research Highlight
  Integrating symbiotic relationship into Escherichia coli
Research Highlight
  Chase of the Walking Proteins
Research Highlight
  Protein Folding by Molecular Chaperone Hsp60 in vitro
Research Highlight
  Actin-Binding Proteins in Polarized Plant Cell Growth
Research Highlight
  Directed Evolution of the Quorum-Sensing Component LuxI
Research Highlight
  Using Bacterial Artificial Chromosomes to Image Motor Proteins at Endogenous Levels During Mitosis
Research Highlight
  Identifying CRABP-I Interactions in vivo via photo-cross linking Research Highlight
  Enhancing Techniques for Single Biomolecule Studies
Research Highlight
  How Do These Motors Move?
Research Highlight
  Obstacles Along Microtubules Alter Biophysical Properties of Motor Proteins
Research Highlight

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University of Massachusetts
Institute for Cellular Engineering
686 North Pleasant Street
159 Goessmann Laboratory
Amherst, MA 01003