UMass Amherst
University of Massachusetts Amherst

Institute for Cellular Engineering

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Kevin Griffith
Assistant Professor, Microbiology
University of Massachusetts
Amherst, MA 01003
(413) 577-1311
griffith@microbio.umass.edu
http://www.bio.umass.edu/micro/faculty/griffith.html


Bacterial cell-cell signaling and engineering tools to study regulatory networks

The main focus of our research is to understand the regulation of biological processes by cell-cell signaling in Bacillus subtilis.  A second focus is to develop tools for studying regulatory networks.  We engineered a controllable protein degradation system that is currently being used to understand the function of several uncharacterized proteins essential for viability in B. subtilis.

 

Research Interest

Potential Application

Bacterial cell-cell signaling

To understand the regulation of important biological processes including:  bioluminescence, antibiotic production, horizontal gene transfer, pathogenesis, and development

Engineering controllable protein degradation systems

Dissecting regulatory networks; studies of essential protein function; controlling the temporal degradation of proteins; and constructing synthetic pathways and genetic switches

 

 

 

 

University of Massachusetts
Institute for Cellular Engineering
686 North Pleasant Street
159 Goessmann Laboratory
Amherst, MA 01003