Bacterial cell-cell signaling and engineering tools to study regulatory networks
The main focus of our research is to understand the regulation of biological processes by cell-cell signaling in Bacillus subtilis. A second focus is to develop tools for studying regulatory networks. We engineered a controllable protein degradation system that is currently being used to understand the function of several uncharacterized proteins essential for viability in B. subtilis.
Research Interest
Potential Application
Bacterial cell-cell signaling
To understand the regulation of important biological processes including: bioluminescence, antibiotic production, horizontal gene transfer, pathogenesis, and development
Engineering controllable protein degradation systems
Dissecting regulatory networks; studies of essential protein function; controlling the temporal degradation of proteins; and constructing synthetic pathways and genetic switches
University of Massachusetts
Institute for Cellular Engineering
686 North Pleasant Street
159 Goessmann Laboratory
Amherst, MA 01003
