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Biochemistry & Molecular Biology CoursesProgram | Faculty | Master's | Doctoral | Courses
523 General BiochemistryStructure and function of biological molecules, especially proteins, lipids, and carbohydrates. Important concepts include bioenergetics, proteins as biological catalysts, and metabolic pathways as interacting regulated systems. Prerequisites: 1 year of general chemistry, 1 year of organic chemistry or 2nd semester concurrently, and Biochm 285. 524 General Biochemistry (2nd sem)An integrated presentation of the biochemistry and molecular biology of cellular interactions. Emphasis on accounting for complex cellular processes in terms of protein structure and regulation of gene expression. Topics include gene structures and techniques for studying them; replication; control of gene expression; post-translational processing; membrane associated energetics; behavior of transport systems; mechanisms of signal transduction; and interactions of cells with extracellular matrix and with other cells. Prerequisite: Biochm 523, Biochm 285 and Biol 283, or comparable courses, strongly recommended. 526 Biochemistry Laboratory (both sem)Modern techniques in experimental biochemistry and molecular biology. Experiments include enzymology, protein purification, and gene expression and organization. Methods include spectrophotometry, polymerase chain reaction, DNA cloning, electrophoresis, protein detection by immunoblot, RNA hybridization, and computer analysis of DNA and protein sequence data. Manipulation of animal, plant, yeast, and bacterial systems. Prerequisite: Biochm 523. Spring semester enrollment restricted to Biochemistry majors. Credit, 4. 623 Advanced General BiochemistryAdvanced treatment of selected topics in biochemistry, with readings
taken from the current literature. Emphasis on experimental approaches
and problem solving. Topics include protein structure-function, protein
folding and modification, enzyme kinetics, and the study of metabolic
processes (pathways and their regulation) with a molecular genetic approach.
Students enrolled in this course are expected to have taken at least a
one-semester course in upper division biochemistry and 642 Advanced Molecular BiologyStructure, biosynthesis, and function of nucleic acids and the translational apparatus. DNA replication; gene organization; chromatin structure; RNA transcription, regulation of gene expression; protein biosynthesis; mRNA, tRNA, and ribosomes. Prerequisite: Biochm 523/524 or equiv-alent. Credit, 4. 691 Departmental SeminarRequired of all graduate students. Credit, 1 each semester. 692 Seminar: Molecular BiologyCredit, 2. 693 Seminar: Signal TransductionCredit, 2. 694 Seminar: Plant Molecular BiologyCredit, 2. 695 Seminar: Developmental BiochemistryCredit, 2. 696 Independent StudyLibrary or laboratory research under direction of faculty member. Credit, 1-6. 699 Master's ThesisCredit, 1-10. 797 Special Topics in BiochemistryTopics of current interest may include hormones, lipids, carbohydrates, glycoproteins and proteoglycans, control mechanisms, protein synthesis, membranes, nucleic acids, biochemical data analysis, and protein-nucleic acid interactions. Prerequisite: Biochm 623. 899 Doctoral DissertationCredit, 18.
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