Associate Professor of Biology
Family Research Scholar 2014-2015

Gerald Downes examines cellular and molecular mechanisms that are essential for neural network function. Epilepsies are the fourth most common neurological disorder in the United States, and many forms are resistant to current treatments. As a family research scholar, Downes will be developing a proposal titled, “Using Zebrafish to Better Understand and Treat Epilepsies.” The aim of this project is to leverage the advantages of zebrafish for rapid genetic and behavioral analysis to develop new animal models of human epilepsies. These new models will be used to investigate cellular and molecular mechanisms disrupted in epilepsies and screen for new antiepileptic drugs. 

CRF Grants:
National Science Foundation: Division of Integrative Organismal Systems

"GABA A Receptor Control of Hyperactivity in Developing Zebrafish"

Collaborative proposal submitted with Amherst College chemistry professor, James Chambers, on August 1, 2014.

Grant Status: Pending
Gerald Downes