Most of MCB’s approximately 100 faculty are in life sciences departments on the UMass Amherst campus. Others are in life sciences departments on the nearby campuses of Smith College, Mount Holyoke College, Hampshire College, and Amherst College. MCB faculty have close relationships with faculty/M.D.s at the Baystate Medical Center in Springfield, Mass., through the UMass/Baystate Collaborative Biomedical Research Program.
- Where do MCB students come from?
- What do MCB students accomplish during their graduate training?
- Where do MCB students go for postdoctoral training or after degree completion?
Currently, 75 students are working toward doctoral degrees and 18 students are pursuing master’s degrees in the MCB program. The strengths of the program are the breadth of its faculty’s research interests, the interdisciplinary nature of its training, and the close mentoring and individual attention MCB students receive. Patricia Wadsworth, Professor of Biology, is the program’s interim director.
Where do MCB students come from?
The MCB graduate program recruits students from various universities in the United States and abroad. Students entering the program within the past three years received their undergraduate degrees from institutions in the following U.S. states:
California—University of Southern California, California Polytechnic State University
Pennsylvania—Pennsylvannia State University, Dickinson College, Marywood University
Washington—University of Washington
New York—State University of New York at Albany
New Hampshire—University of New Hampshire
Vermont—Saint Michael’s College, University of Vermont
Massachusetts—UMass Amherst, Mount Holyoke College, Clark University, Massachusetts Institute of Technology And from the following foreign institutions:
What do MCB students accomplish during their graduate training?
- McGill University, Montreal, Canada
- University of Kashmir, India
- Fudan University, Shanghai, China
- National Taiwan University, Taiwan
- Korea University, South Korea
- Universidad Nacional de Quilmes, Argentina
- Bilkent University, Ankara, Turkey
The following is a selected list of student publications dated 2000-2007, of which majority are first author publications.
- Li M, and Schnell DJ. Reconstitution of protein targeting to the inner envelope membrane of chloroplasts. J Cell Biol. 2006 Oct 23;175(2):249-59. **Article Highlighted on the Cover
- David Sharlin, Ruby Bansal, R. Thomas Zoeller. Polychlorinated Biphenyls Exert Selective Effects on Cellular Composition of White Matter in a Manner Inconsistent with Thyroid Hormone Insufficiency. Endocrinology, February 2006. Volume 147 (2): 846-858.
- C. Marcelino, R. G. Smock, and L. M. Gierasch, Evolutionary Coupling of Structural and Functional Sequence Information in the Intracellular Lipid-Binding Protein Family, Proteins: Structure Function Bioinformatics, 63, 373-384 (2006).
- R. G. Smock and L. M. Gierasch, Finding the Fittest Fold: Using the Evolutionary Record to Design New Proteins, Cell, 122, 832-834 (2005).
- Hsu YC, Willoughby JJ, Christensen AK, and Jensen AM. 2006. Mosaic eyes is a novel component of the crumbs complex and negatively regulates photoreceptor apical size. Development 133(24):4849-59.
- You SH, Gauger KJ, Bansal R, Zoeller RT. 4-Hydroxy-PCB106 acts as a direct thyroid hormone receptor agonist in rat GH3 cells. Mol Cell Endocrinol. 2006 Sep 26; 257-258:26-34.
- Renzette N, Gumlaw N, Nordman JT, Krieger M, Yeh SP, Long E, Centore R, Boonsombat R, Sandler SJ. 2005. Localization of RecA in Escherichia coli K-12 using RecA-GFP. Mol Microbiol. 4:1074-85.
- Tulu, U.S., Fagerstrom, C., Ferenz, N.P. and Wadsworth, P. 2006. Molecular requirements for kinetochore-associated microtubule formatin in mammalian cells. Current Biology. 16:536-541.
- Murthy, K. and Wadsworth, P. (2005). Myosin-II-dependent localization and dynamics of F-actin during cytokinesis. Curr. Biol., 15, 724-731.
- Rusan, N. M. and Wadsworth, P. (2005). Centrosome fragments and microtubules are released and transported asymetrically away from division plane in anaphase. J. Cell Biol., 168, 21-28.
- Tulu, U. S., Rusan, N. M., and Wadsworth, P. (2003). Peripheral, non-centrosome-associated microtubules contribute to spindle formation in centrosome-containing cells. Curr. Biol., 13, 1894-1899
- Rusan, N. M., Tulu, U. S., Fagerstrom, C., and Wadsworth, P. (2002). Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport. J. Cell Biol., 158, 997-1003.
- Rusan, N. M., Fagerstrom, C. J., Yvon, A. C., and Wadsworth, P. (2001). Cell cycle-dependent changes in microtubule dynamics in living cells expressing GFP-alpha tubulin. Mol. Biol. Cell, 12, 971-980.
- Brennan KM, Vella KR, Good DJ. 2006. Genetic analysis of NHLH2 and its putative role in bovine body weight control. Anim Genet. Aug;37 Suppl 1:24-27
- Francis, E., Daniels, R., Hebert, D.N. (2002). Analysis of Protein Folding and Oxidation in the Endoplasmic Reticulum. In Current Protocols in Cell Biology. M.D. Bonafacino J, Lippincott-Schwartz, J, Hartford, J.B., & Yamada, K.M. (Eds.). New York: John Wiley and Sons Inc. 15.6.1-15.6.29.
- Daniels, R., Kurowski, B., Johnson, A.E., Hebert, D.N. (2003). "N-linked glycans direct the co-translational folding pathway of Influenza Hemagglutinin." Molecular Cell, 11:79-90.
- Daniels, R., Svedine, S., Hebert, D.N. (2004). "N-linked Carbohydrates as Lumenal Maturation and Quality Control Protein Tags." Cell Biochemistry and Biophysics, 41:113-137.
- Wang, N., Daniels, R., Hebert, D.N. (2005). "The Co-translational Maturation of the Type I Membrane Glycoprotein Tyrosinase: The Heat Shock Protein 70 System Hands Off to the Lectin-based Chaperone System." Molecular Biology of the Cell, 16(8):3740-52.
- Daniels, R., Rusan, N.M., Wilbuer, A.K., Norkin, L.C., Wadsworth, P., Hebert, D.N. (2006). “Simian virus 40 late proteins possess lytic properties that render them capable of permeabilizing cellular membranes.” Journal of Virology, 80(13):6575-87. ** Data from this paper was chosen for the Journal of Virology Cover (2006). Volume 80, Issue 23.**
- Daniels, R., Rusan, N.M., Wadsworth, P., Hebert, D.N. (2006). “SV40 minor structural proteins VP2 and VP3 perform major roles in cell binding and penetration.” Molecular Cell, 24:955-66.
Where do MCB students go for postdoctoral training or after degree completion?
- Zhang J, Tu Y, Schneider SS. Activation of p53, inhibition of telomerase activity, and induction of estrogen receptor beta are associated with the anti-growth effects of combination ovarian hormones and retinoids in immortalized human mammary epithelial cells. Cancer Cell International, 2005, 5(6).
- Tu Y, Pazik B, Jerry DJ, Schneider SS. Sensitivity to DNA damage is a common component of hormone based strategies for protection of the mammary gland. Molecular Cancer Research, 2005 Aug, 3(8): 435-42.
- Allison Craney, Sheean Haley, and Sonya Dyhrman. Oct 2004. Alkaline phosphatase activity in the toxic dinoflagellate Karenia brevis. Biol Bull. 207: 174
- Wang N, Daniels R, Hebert DN. The cotranslational maturation of the type I membrane glycoprotein tyrosinase: the heat shock protein 70 system hands off to the lectin-based chaperone system. Mol Biol Cell. 2005 Aug;16(8):3740-52. Epub 2005 Jun 15.
- Remy Chait, Allison Craney, and Roy Kishony. 2007. Antibiotic combinations that generate selective competition against resistance. Nature, in press.
Our graduates have gone on to postdoctoral research positions at academic research institutions or in the biotechnology industry in the U.S. and abroad. Some of our graduates have taken positions at the following institutions (see Our Graduates page for specific information):
- Cold Spring Harbor Laboratory
- University of North Carolina
- Duke University
- Dana-Faber Cancer Institute
- National Cancer Institute
- Johnson & Johnson
- Eli Lilly