Young-Cheul Kim

Assistant Professor

Telephone: 413-577-4553
Email: yckim@nutrition.umass.edu
Campus Address: 206-B Chenoweth

Ph.D., Nutrition Science, University of Tennessee
M.S., Food Science & Technology, Korea University
B.S., Biology, Keimyung University
Postdoc., Pharmacology & Biochemistry, Univ. of Wisconsin-Madison

Research Interests:

My research interest is to understand how nutrients and dietary bioactive components (i.e., phytochemicals) contribute to chronic diseases such as obesity and diabetes by determining the molecular factors/pathways involved in fat cell differentiation and metabolism.

Selected Publications:

Kwon, Y-I., Apostolidis, E., Kim, Y-C. and Shetty, K. Health benefits of traditional corn, beans and pumpkin; In vitro studies for hyperglycemia and hypertension management. J. Medicinal Foods. Accepted for publication

Lee O-K, Kim Y-C, Kim KJ, Kim Y, and Lee BY. The effects of bioactive compounds and fatty acvid compositions on the oxidative stability of extra virgin olive oil varieties. Food Science and Biotechnology. Accepted for publication

Davis J, Higginbotham A, O'connor T, Moustaid-Moussa N, Tebbe A, Kim Y-C et al. Soy Protein and Isoflavones Influence Adiposity and Development of Metabolic Syndrome in the Obese Male ZDF Rat. Ann Nutr Metab. 51: 42-52, 2007.

Kim KJ, Lee O-K, Lee HC, Kim Y-C, and Lee BY. Effect of Fucoidan on Expression of Diabetes Mellitus Related Genes in Mouse Adipocytes. Food Science and Biotechnology. Vol. 16 No. 2, p49-54, 2007.

Zhao, D, Duan, H, Kim, Y-C, Jefcoate, CR. Rodent StAR mRNA is substantially regulated by control of mRNA stability through sites in the 3’-untranslated region and through coupling to ongoing transcription. Journal of Steroid Biochemistry & Molecular Biology. 96:155-173, 2005.

Kim, Y-C. Regulation of Fat Cell Development and Gene Expression. Proceeding of 4th International Symposium of APRC – Molecular Biology and Agriculture, pp1-8. 2003.

Gomez FE, Miyazaki M, Kim Y-C, Marwah P, Lardy HA, Ntambi JM, Fox B. Molecular differences caused by differentiation of 3T3-L1 preadipocytes in the presence of either dehydroepiandrosterone (DHEA) or 7-oxo-DHEA. Biochemistry. 41: 5473-5482, 2002.

Miyazaki, M, Kim, Y-C, and Ntambi, J.M. A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis. Journal of Lipid Research. 42: 1018-1024, 2001.

Ntambi, J.M. and Kim, Y-C. Regulation of the stearoyl-CoA desaturase genes by dietary fat: Role of polyunsaturated fatty acids. "Nutrient-Gene Interactions in Health and Disease". CRC Series in Modern Nutrition. pp49-61, 2001.

Kim, Y-C, Ntambi, J.M., Gomez, E., and Fox, B.G. Differential Regulation of the Stearoyl-CoA Desaturase Genes by Thiazolidinediones in 3T3-L1 Adipocytes. Journal of Lipid Research. 41 (8): 1310-1316, 2000.

Makoto, M, Kim, Y-C, Keller,M.P., Attie, A.D., and Ntambi, J.M.The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1. Journal of Biological Chemistry. 275 (39): 30132-30138, 2000.

Kim, Y-C and Ntambi, J.M. Regulation of Stearoyl-CoA Desaturase genes: Role in cellular metabolism and preadipocyte differentiation. Biochem. Biophys. Res. Comm. 266 (1): 1-4, 1999.