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| MARC
J. TETEL |
Bio |
Research |
Publications |
Lab Members |
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| Dr.
Tetel's general research area is studying
how the ovarian steroid hormones, estradiol
and progesterone, act in the brain to regulate
gene expression and female reproductive behavior
in rodents. These hormones elicit many of
their effects on reproduction by binding to
their respective intracellular receptors located
in specific brain regions. Recently, nuclear
receptor coactivators have been found to dramatically
enhance the transcriptional activity of steroid
receptors. Dr. Tetel is exploring how these
coactivators function with steroid receptors
in brain to activate behaviorally-relevant
genes. His research uses immunohistochemical
and Western blot techniques to analyze neural
protein expression and antisense technology
to explore the function of these coactivators
in brain.
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