CBI RELATED SEMINARS-SPRING 2008

Tuesday, February 5 – MCB
A. Clay Clark, NC State University
Death by Caspase Dimerization
Host: Jeanne Hardy

Thursday, February 7 - Chemistry
John R. Engen, Department of Chemistry and Chemical Biology, Northeastern University
Measuring Cooperative Unfolding in Proteins and its Application in the Study of SRC-Family Kinase Regulatory Mechanisms
Host: Igor Kaltashov

Tuesday, February 12 – MCB
David B. Goodin, The Scripps Research Institute
Probing the Substrate Binding Site of Heme Enzymes with Molecular Wires
Host: Michael Knapp

Thursday, February 21 - Chemistry
Babis Kalodimos, Department of Chemistry, Rutgers University
Structural Basis for the Assembly of Large Protein Machineries Determined by NMR: The Sec Translocase Machinery
Host: Lila Gierasch

Tuesday, February 26 – MCB
Ning Zheng, University of Washington
Ubiquitin Ligase Machinery: From Plant Biology to Human Diseases
Host: Scott Garman

Thursday, February 28 - Chemistry/CBI Student Invited Speaker
Lars Konermann, Department of Chemistry and Biochemistry,
University of Western Ontario
Using Electrospray Mass Spectrometry for Exploring Protein Folding and Dynamics
Host: Vanessa Mendoza (Vachet Group)

Friday, February 29 - PSE
Paul Cremer, Texas A&M University
Using Bilayers as a Nanoscale Separation Matrix
Host: Maria Santore

Tuesday, March 4 - MCB
Evan T. Powers, The Scripps Research Institute
Protein Folding, Misfolding, and Export from Cells
Host: Lila Gierasch

Thursday, March 6 - Chemistry
Lola Reid, Cell and Molecular Physiology, University of North Carolina at Chapel Hill
Ex Vivo Conditions for Self-replication, Lineage Restriction versus Differentiation of Human Hepatic Stem Cells
Host: Paul Dubin

Saturday, March 8 – Annual MCB Retreat
James L. Keck, University of Wisconsin-Madison
(Former Biochemistry Undergraduate here at UMass)
Structural Mechanisms of Genome Maintenance
Host: Steve Sandler

Tuesday, March 11 – MCB
Gregory A. Petsko, Brandeis University
Structural Neurology - An Approach to the Understanding, Treatment and Prevention of Neurodegenerative Diseases
Host: Scott Garman

Thursday, March 13 - Chemistry
John D. Lipscomb, Department of Biochemistry, Molecular Biology and Biophysics University of Minnesota
Seeing Oxygen Activation Through a Crystalline Lens
Host: Michael Knapp

Friday, March 21 - PSE
Frederic Pincet, Ecole Normale Supérieure
Molecular and Cellular Mechanisms from Force Measurements: SNARE Mediated Fusion and Cadherin-Integrin Crosstalk
Host:  Maria Santore

Wednesday, March 26 - Chemistry
Christopher M. Cheatum, Department of Chemistry,
University of Iowa
Watching the Protein Mambo: Fast Enzyme Dynamics
Host: Michael Knapp

Thursday, March 27 - Chemistry
Gavin Reid, Department of Chemistry, Michigan State University
Chemical Methods for Selective Proteome Analysis
Host: Richard Vachet

Tuesday, April 1 – MCB
Frederick R. Maxfield, Weill Cornell Medical College
Sterol Distribution and Transport in Cells
Host: Alejandro Heuck

Thursday, April 3 - Chemistry
Professor Patrick Loria, Department of Chemistry, Yale University
Biophysical Characterization of Important Enzyme Motions
Host: Lynmarie Thompson

Thursday, April 10 - Chemistry
Professor Jim Mayer, Department of Chemistry, University of Washington
Oxidations of O-H and C-H Bonds:From Hydrogen Atom Transfer to Proton-Coupled Electron Transfer
Host: Michael Maroney

Tuesday, April 15 – MCB
Sarah E. O'Connor, Massachusetts Institute of Technology
Alkaloid Biosynthesis in Periwinkle
Host: Jennifer Normanly

Thursday, April 17 Chemistry
Allen Minton, Physical Biochemistry Section, Chief, NIDDK,
National Institutes of Health
How Biochemistry In Vivo can Differ from Biochemistry In Vitro
Host: Lila Gierasch

Tuesday, April 22 - Chemistry/FIVE COLLEGE SEMINAR
Roger Y. Tsien
Department of Pharmacology and Chemistry and Biochemistry,
University of California, San Diego
Building Molecules to Spy on Synapses and Tumors
Host: Five College, UMass Amherst

Tuesday, April 29 - MCB
Stephen C. Blacklow, Harvard Medical School
Mechanistic Insights into Normal and Pathogenic Notch Signaling
Host: Jenny Maki (Gierasch group)

Tuesday, May 6 - MCB
Douglas C. Rees, California Institute of Technology
ABC Transporter Structure and Mechanism
Host: Lynmarie Thompson

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