The University of Massachusetts Amherst

Wei Cui

Extension Assistant Professor, Director of Animal Models Core

Research areas include mammalian oocyte maturation and activation, preimplantation embryo development, micromanipulation and animal model generation.

Current Research

Current research in my laboratory aims at: 1) understanding the cellular and molecular mechanisms underlying mammalian oocyte meiosis, activation, and aging; 2) discovering novel genes, factors, and signaling pathways that are functionally required during mammalian preimplantation embryo development; 3) creating animal models of human genetic diseases using knock-out, knock-in, and transgenesis strategies.

Learn more at www.vasci.umass.edu/research-faculty/wei-cui

Academic Background

  • Postdoctoral Training, University of Massachusetts Amherst, 2014-2017
  • Postdoctoral Training, University of Kansas Medical Center, 2013-2014
  • Ph.D, Shandong Agricultural University, China, 2013
Cui W. SOHLHs are essential for fertility regardless of gender or population. Fertil Steril 2020; 114:283-284.
Miao X, Sun T, Barletta H, Mager J, Cui W. Loss of RBBP4 results in defective inner cell mass, severe apoptosis, hyperacetylated histones and preimplantation lethality in micedagger. Biol Reprod 2020; 103:13-23.
Cui W, Cheong A, Wang Y, Tsuchida Y, Liu Y, Tremblay KD, Mager J. MCRS1 is essential for epiblast development during early mouse embryogenesis. Reproduction 2020; 159:1-13.
Jiang Z, Cui W, Prasad P, Touve MA, Gianneschi NC, Mager J, Thayumanavan S. Bait-and-Switch Supramolecular Strategy To Generate Noncationic RNA-Polymer Complexes for RNA Delivery. Biomacromolecules 2019; 20:435-442.
Jiang Z, Cui W, Mager J, Thayumanavan S. Postfunctionalization of noncationic RNA–polymer complexes for RNA delivery. Industrial & Engineering Chemistry Research 2019; 58(17):6982–6991.
 
Contact Info

Department of Veterinary & Animal Sciences
S521 Life Science Laboratories
240 Thatcher Way
Amherst, MA 01003-9292

(413) 545-0673
wcui@umass.edu

umass.edu/ials/animal-models