David A. Sela
Our research seeks to better understand the mechanisms by which nutritive molecules promote health. We seek to solve chronic diseases primarily through preventative dietary and lifestyle adjustments.
We use sequence-based genomic approaches to investigate the structure and function of microbial communities within the gut. These ecosystems are often collectively referred to as the human microbiome. In addition, we investigate mechanistic linkages between food and health emanating from host-microbial molecular interactions.
We view microbes as the vehicle to deliver bioactive molecules, the bioactives themselves to be delivered, as well as the endogenous targets to manipulate in the human gastrointestinal tract. To address the latter, we investigate molecules derived from food to dictate the function of beneficial subpopulations within the gut. Our primary model in this endeavor is breast milk and its role in guiding the infant gut microbiome. Moreover, we seek to innovate the next generation of orally administered microbes, commonly referred to as probiotics. To this end, we seek partnerships with industrial and clinical partners in order to translate the scientific knowledge of our research activities.
Learn more at www.selalab.org
- BS State University of New York, New Paltz, 2003
- MS University of California, Davis, 2006
- PhD University of California, Davis 2010
- Postdoctoral Training: Stanford University
- Postdoctoral Training: Foods for Health Institute, University of California, Davis