A graduate student’s surprise observation in fundamental experiments with small binding molecules at work in protein folding has allowed biochemists at the University of Massachusetts Amherst to develop the first firm mathematical foundation to explain cell ligands’ role in promoting proper protein folding. More.
UMass Amherst biochemists say small molecules have big influence in protein folding
Scott Garman named 2017 Public Engagement Faculty Fellow
Two CNS faculty members have been named 2017 Public Engagement Faculty Fellows by the Public Engagement Project (PEP): Julie Brigham-Grette, Geosciences and Scott Garman, Biochemistry and Molecular Biology. Along with five other PEP faculty members, they will draw on their substantial research record to impact policy, the work of practitioners and public debates. The fellows, who will receive a stipend and technical training in communicating with non-academic audiences, will also travel to Beacon Hill to share their research with lawmakers. Read More Here.
UMass Amherst and Boston-based PCL, Inc. offer new tool for biotech research
Stewards of the university's plant cell culture library, including Jennifer Normanly, Elizabeth Vierling, Li-Jun Ma, all Biochemistry and Molecular Biology, and Tristram Seidler, Biology, recently announced a new collaboration with the South Korean biotechnology company PCL, Inc. of Seoul and Boston, to provide users worldwide with a new technology for accurate, highly sensitive target-molecule detection in chemically complex plant samples. Read More.
Lila Gierasch Inducted into the American Academy of Arts and Sciences
Press release for Lila Gierasch's induction into the American Academy of Arts and Sciences.
Chien Lab Publishes Paper in Molecular Microbiology: The Many Paths of Destruction
The timely degradation of proteins is necessary for life. In the model bacterium Caulobacter crescentus, destruction of the replication initiator protein DnaA by the Lon protease is important for stress responses. New work from the Chien lab now published in Molecular Microbiology (http://onlinelibrary.wiley.com/doi/10.1111/mmi.13537/abstract) has revealed that an auxiliary protease pathway is also involved in controlling DnaA. Limiting the accumulation of this essential factor is critical as too much replication is toxic under the incorrect conditions. The ability of cells to use two proteolytic pathways to control an essential replication factor is an excellent strategy to ensure robust control under different growth conditions.
Professor Gershenson to Deliver Invited Talk Titled "In Silico to In-Cell Folding of Metastable Serpins" at the 30th Anniversary Symposium of the Protein Society
Profs. Gershenson, Gierasch and Hebert Untangle Disease-Related Protein Misfolding
Dong Wang and Li-Jun Ma Recognized for Research at International Meeting
Dong Wang and Li-Jun Ma were recognized for their research at the 17th International Congress of the International Society for Molecular Plant-Microbe Interactions in Portland, Oregon. This meeting highlights research areas including the microbiome, tritrophic interactions, RNA-mediated interactions, systems biology, resistance mechanisms, mutualism and microbial virulence functions. Read More.
UMass Amherst Announces 2016 ‘Armstrong Fund for Science’ Awards
A team of four University of Massachusetts Amherst researchers are the Armstrong Fund for Science winners for 2016. This winning team consists of faculty from the departments of biochemistry and molecular biology and microbiology, including Li-Jun Ma, a fungal biologist recently named as a Burroughs Wellcome Fund investigator in the pathogenesis of infectious disease, Sergey Savinov, a chemist, and two microbiologists, Michele Klingbeil and Yasu Morita. Read more.
UMass Amherst Biological Chemist Lila Gierasch Elected to American Academy of Arts and Sciences
The American Academy of Arts and Sciences announced the election of 213 new members, including biological chemist Lila Gierasch, Distinguished Professor at the University of Massachusetts Amherst, along with some of the world’s most accomplished scholars, scientists, writers, artists and civic, business and philanthropic leaders. Read more.
Lila Gierasch Named New Editor in Chief of Journal of Biological Chemistry